Kinases are key targets in therapeutic research, but traditional methods often overlook their activity, focusing instead on protein presence. This limits our understanding of cell signaling and the mechanisms of action, especially in compound interactions. Screening for active kinases provides deeper, more actionable insights.
With 18 years of experience, PamGene has led the way in developing a unique technology that offers unparalleled sensitivity for real-time measurement of kinase activity. The multiplexing capabilities of our chips (PTK & STK) provide a holistic view of cellular signalling, encompassing over 380+ cellular kinases. This breakthrough technology not only reveals changes in signalling activity, but also facilitates the creation of kinase-based biomarkes response predictions assay (IOpener® CE-IVD Immunotherapy guidance tests).
Applications of this technology are diverse and include pathway elucidation, target discovery, mechanism of action studies, resistance mechanism analysis, immune cell characterization, clinical research, prognostic biomarker identification and therapeutic response assessment.
If you’re unsure how this fits into your research? Let’s set up an online meeting to discuss how our approach can enhance your project. Sales@pamgene.com
When submitting your proposal, please ensure that you include the following:
Note for Designing Your Project:
To design your project effectively, please provide the following information:
Please do not hesitate to contact the PamGene team at email@example.com for inquiries or to explore the possibilities of Kinome Profiling technology. We are committed to assisting you in establishing a research proposal that ensures success.
Simply pitch and submit your research project proposal by either:
To write your research proposal, here are the essential guidelines.
The winner will receive a complimentary Kinase Activity Profiling Service from PamGene aligned with their research objectives.
The prize winner will be announced after the 30th of April – 2024