We offer Contract Research Services tailored to your needs and research questions.
Broad interrogation of the full range of kinases (~350) and screen for a match between your identified compound and a kinase resulting in a set of lead kinase inhibitors.
Improvement and specification of your clinical trials through dividing your potential patient group into kinase related subgroups.
Comparative analysis of your diseases model (in vitro or in vivo and human or rodent) with respect to healthy or wild type counterpart to gain disease specific kinome or signal transduction related information
Ibrahim AN, Yamashita D, Anderson JC, Abdelrashid M, Alwakeal A, Estevez-Ordonez D, Komarova S, Markert JM, Goidts V, Willey CD, Nakano I.
J Neurosurg. Oct 18:1-12.(2019)
de Korte T, Nacken P, Pijnenburg D, Ruijtenbeek R, Stevenhagen F, Wilbers R, den Hartogh S, Groten J, Braam S and Vlaming M
Journal of Pharmacological and Toxicological Methods. 88. 236-237. 10.1016. (2017)
Sawada T, Hilhorst R, Rangarajan S, Yoshida M, Tanabe Y, Tamura K, Kinoshita T, Shimoyama T, van Beuningen R, Ruijtenbeek R, Tsuda H, Koizumi F
Oncotarget. Sep 28;9(76):34229-34239. (2018)