Our white paper (free download) describes trends over a decade of small molecule Protein Kinase Inhibitor (PKI) research by mining thousands of American Society for Cancer Research (AACR) abstracts covering the period of 2004-2013. You can access relevant information relating to drug discovery and research that could be important for you!
![](https://pamgene.com/wp-content/uploads/2020/03/AACR-Whitepaper-Targets-graph.png)
The paper describes research on:
- 26 approved PKIs and other DrugBank drugs
- over 300 PKI’s of over 90 companies and institutes with the top-4 companies being Pfizer, Novartis, AstraZeneca and GlaxoSmithKline
- up to 69 kinase targets with a top-4 of EGFR, HER, PDGFR and VEGFR covering more than 50% of targeted kinase
A sample figure below shows that the number of kinase small molecule inhibitor drugs described each year has tripled from 40 to 120:
![](https://pamgene.com/wp-content/uploads/2020/03/AACR-Whitepaper-PKI-Figure.png)
![](https://pamgene.com/wp-content/uploads/2020/03/AACR-Whitepaper-PKI-Figure.png)
Download the Whitepaper:
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